Differential reward network functional connectivity in cannabis dependent and non-dependent users
نویسندگان
چکیده
منابع مشابه
Differential reward network functional connectivity in cannabis dependent and non-dependent users.
BACKGROUND Emergent studies show that similar to other substances of abuse, cue-reactivity to cannabis is also associated with neural response in the brain's reward pathway (Filbey et al., 2009). However, the inter-relatedness of brain regions during cue-reactivity in cannabis users remains unknown. METHODS In this study, we conducted a series of investigations to determine functional connect...
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Research suggests that daily cannabis users have impaired memory for past events, but it is not clear whether they are also impaired in prospective memory (PM) for future events. The present study examined PM in daily cannabis users who were either dependent (n = 18) or non-dependent (n = 18), and compared them with non-using controls (n = 18). The effect of future event simulation (FES) on PM ...
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Although altered function in neural reward circuitry is widely proposed in models of addiction, more recent conceptual views have emphasized the role of disrupted response in prefrontal regions. Changes in regions such as the orbitofrontal cortex, medial prefrontal cortex, and dorsolateral prefrontal cortex are postulated to contribute to the compulsivity, impulsivity, and altered executive fun...
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متن کاملReduced response to reward in smokers and cannabis users.
BACKGROUND Cannabis is one of the most commonly used illicit drugs. Reduced neural and behavioral reactions to reward have been demonstrated in other forms of addiction, as expressed by reduced mood reactivity and lack of striatal activation to rewards, but this effect has not yet been investigated in cannabis users. METHODS We hypothesized that cannabis users and tobacco smokers would eviden...
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ژورنال
عنوان ژورنال: Drug and Alcohol Dependence
سال: 2014
ISSN: 0376-8716
DOI: 10.1016/j.drugalcdep.2014.04.002